2012 Small World In Motion Competition

Artboard 1

1st Place

2012 Small World In Motion Competition

Recruitment of neutrophils to the site of laser damage in mouse inguinal lymph node

Dr. Olena Kamenyeva

Affiliation
National Institutes of Health (NIH)
NIAID - Laboratory of Immunoregulation
Bethesda, Maryland, USA
Technique
2-photon

This video shows the immune response in the lymph node of a mouse, when activated by a laser. Specifically, it shows an efficient innate immune reaction in the lymph node, which typically has been studied for the development of adaptive immune response.

2nd Place

2012 Small World In Motion Competition

Sperm from two males competing within reproductive tract of a female fruit fly (Drosophila melanogaster)

Dr. Stefan Lüpold

Affiliation
Syracuse University
Department of Biology
Syracuse, New York, USA
Technique
Fluorescence
Magnification
400x

Sperm of two different males (green and red) competing within the female reproductive tract of the fruit fly Drosophila melanogaster. Competition between sperm is a widespread phenomenon throughout the animal kingdom and a powerful evolutionary force driving species diversity. However, it has been nearly impossible to study the fundamental biological processes associated with such sperm competition, occurring whenever sperm from different males mix inside of females. The very recent development of genetically modified fruit flies that produce sperm with either green- or red-fluorescent heads (as seen in the movie) is now allowing us to answer important biological questions.